A Molecular Profile of the Endothelial Cell Response to Ionizing Radiation
نویسندگان
چکیده
منابع مشابه
Cellular response to ionizing radiation: A microRNA story
MicroRNAs (miRNAs) represent a class of small non-coding RNA molecules that regulate gene expression at the post-transcriptional level. They play a crucial role in diverse cellular pathways. Ionizing radiation (IR) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. Recently it has been discovered that mi...
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Astronauts participating in long duration space missions are likely to be exposed to ionizing radiation associated with highly energetic and charged heavy particles. Previously proposed gene biomarkers for radiation exposure include phosphorylated H2A Histone Family, Member X (γH2AX), Tumor Protein 53 (TP53), and Cyclin-Dependent Kinase Inhibitor 1A (CDKN1A). However, transcripts of these genes...
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OBJECTIVES Vasculature damage is an important contributor to the side-effects of radiotherapy. The aim of this study is to provide insights into the radiobiology of the autophagic response of endothelial cells. METHODS AND MATERIALS Human umbilical vascular endothelial cells (HUVEC) were exposed to 2 Gy of ionizing radiation (IR) and studied using confocal microscopy and western blot analysis...
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micrornas (mirnas) represent a class of small non-coding rna molecules that regulate gene expression at the post-transcriptional level. they play a crucial role in diverse cellular pathways. ionizing radiation (ir) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. recently it has been discovered that mi...
متن کاملResponse of Cells to Ionizing Radiation
Ionizing radiation is encountered in our natural environment and is also generated and used by mankind, e.g., for medical uses. A better understanding of the biological effects of ionizing radiation will lead to better use of and better protection from radiation. In this chapter, the response of cells to radiation will be described and discussed. Some basic concepts of ionizing radiation will b...
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ژورنال
عنوان ژورنال: Radiation Research
سال: 2016
ISSN: 0033-7587
DOI: 10.1667/rr14444.1